Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868028 | 0.92 | GAA (0.48) | GAAHDAC1HDAC6MAPK1BRAF | |
| SCHEMBL1203927 | 0.86 | GAA (0.50) | GAAHDAC1HDAC6MAPK1BRAF | |
| SCHEMBL23948693 | 0.85 | GAA (0.46) | GAAHDAC1HDAC6MAPK1BRAF | |
| SCHEMBL29501882 | 0.85 | GAA (0.46) | GAAHDAC1HDAC6MAPK1BRAF | |
| SCHEMBL7981477 | 0.84 | GAA (0.55) | GAAHDAC1HDAC6MAPK1POLB | |
| SCHEMBL15939166 | 0.81 | GAA (0.46) | GAAHDAC1HDAC6MAPK1BRAF | |
| SCHEMBL23243142 | 0.81 | GAA (0.46) | GAAHDAC1HDAC6BRAFALOX5AP | |
| SCHEMBL31080125 | 0.81 | GAA (0.46) | GAAHDAC1HDAC6BRAFALOX5AP | |
| SCHEMBL13575580 | 0.81 | KDM4E (0.47) | GAAHDAC1BRAFPOLBKDM4E | |
| SCHEMBL23266520 | 0.80 | POLB (0.50) | GAAHDAC1HDAC6POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4640678-A1 | NOVEL OXO-PYRIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Chengdu Shibeikang Biomedical Technology Co., Ltd. (CN) | 2025-10-29 | — | — | EP | disclosed |
| CN-116082303-B | Novel oxopyridines, intermediates and uses thereof | 成都施贝康生物医药科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| WO-2024131841-A1 | NOVEL OXO-PYRIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 成都施贝康生物医药科技有限公司 | 2024-06-27 | — | — | WO | disclosed |
| CN-116082303-A | Novel oxopyridines, intermediates and uses thereof | 成都施贝康生物医药科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| WO-2009153197-A1 | HALO-SUBSTITUTED PYRIMIDODIAZEPINES AS PLKL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-12-23 | — | — | WO | disclosed |