SCHEMBL13580411

CC(C)(C)C1=CC(=C/N=N/c2cc(Cl)cc(-c3cc(Cl)cc(/N=N/C=C4C=C(C(C)(C)C)C(=O)C(C(C)(C)C)=C4)c3Cl)c2Cl)C=C(C(C)(C)C)C1=O

nearest known ligand 0.33

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	NPC1	O15118	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	ATM	Q13315	1/20	0.33

▸	GPR35	Q9HC97	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13580430	0.92	—	—
SCHEMBL13580861	0.91	—	—
SCHEMBL13580318	0.85	NPC1 (0.34)	NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580424	0.84	NPC1 (0.36)	NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580420	0.84	NPC1 (0.36)	NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580417	0.83	NPC1 (0.34)	NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL24543460	0.82	CTDSP1 (0.36)	NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL18877736	0.81	ATM (0.36)	NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580309	0.80	NPC1 (0.34)	NPC1KMT2AATMGPR35SMN1; SMN2
SCHEMBL13580311	0.80	NPC1 (0.34)	NPC1KMT2AATMGPR35SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20090317733-A1	Quinone Compound, Electrophotographic Photoconductor and Electrophotographic Apparatus	FUJI ELECTRIC DEVICE TECHNOLOGY CO., LTD. (JP)	2009-12-24	—	—	US	disclosed
US-20090317733-A1	Quinone Compound, Electrophotographic Photoconductor and Electrophotographic Apparatus	FUJI ELECTRIC DEVICE TECHNOLOGY CO., LTD. (JP)	2009-12-24	—	—	US	disclosed