Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 10/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.41 |
| ▸ | CLPP | Q16740 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13583205 | 1.00 | MEN1 (0.48) | MEN1KMT2AKCNA5ITGB1ITGA4 | |
| SCHEMBL13583789 | 0.92 | MEN1 (0.45) | MEN1KMT2AKCNA5ITGB1ITGA4 | |
| SCHEMBL13583785 | 0.92 | MEN1 (0.45) | MEN1KMT2AKCNA5ITGB1ITGA4 | |
| SCHEMBL2334402 | 0.90 | UTS2R (0.42) | MEN1KMT2AKCNA5ITGB1ITGA4 | |
| SCHEMBL2334406 | 0.90 | UTS2R (0.42) | MEN1KMT2AKCNA5ITGB1ITGA4 | |
| SCHEMBL13583525 | 0.90 | MEN1 (0.43) | MEN1KMT2AKCNA5ITGB1ITGA4 | |
| SCHEMBL13583516 | 0.90 | MEN1 (0.43) | MEN1KMT2AKCNA5ITGB1ITGA4 | |
| SCHEMBL13583111 | 0.88 | MEN1 (0.46) | MEN1KMT2AKCNA5ITGB1ITGA4 | |
| SCHEMBL13583698 | 0.86 | MEN1 (0.46) | MEN1KMT2A | |
| SCHEMBL13583693 | 0.86 | MEN1 (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2524686-B1 | PIGMENTATION-PREVENTING OR -AMELIORATING AGENT | POLA CHEM IND INC (JP) | 2017-06-21 | — | — | EP | disclosed |
| US-9066914-B2 | Prophylactic or ameliorating agent for pigmentation | POLA CHEMICAL INDUSTRIES INC. (JP) | 2015-06-30 | — | — | US | disclosed |
| EP-2524686-A1 | PIGMENTATION-PREVENTING OR -AMELIORATING AGENT | Pola Chemical Industries Inc. (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20120282203-A1 | PROPHYLACTIC OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120282203-A1 | PROPHYLACTIC OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, NQO1 | MEN1 1487/4885KMT2A 1659/4885KCNA5 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.