Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29684521 | 1.00 | MAPT (0.47) | MAPTPOLBMEN1KMT2APKM | |
| SCHEMBL28435570 | 0.80 | MAPT (0.43) | MAPTPOLBMEN1KMT2ARAB9A | |
| SCHEMBL2664539 | 0.78 | KDM4E (0.45) | MAPTPOLBMEN1KMT2APKM | |
| SCHEMBL28695833 | 0.78 | MAPT (0.39) | MAPTPOLBMEN1KMT2APKM | |
| SCHEMBL27803434 | 0.76 | MAPT (0.49) | MAPTPOLBRAB9ALMNANPC1 | |
| SCHEMBL29580092 | 0.76 | MAPT (0.50) | MAPTPOLBMEN1KMT2ARAB9A | |
| SCHEMBL10936934 | 0.76 | MAPT (0.50) | MAPTPOLBMEN1KMT2ARAB9A | |
| SCHEMBL12426895 | 0.74 | MAPT (0.47) | MAPTPOLBRAB9ALMNAALDH1A1 | |
| SCHEMBL169463 | 0.74 | MAPT (0.47) | MAPTPOLBMEN1KMT2ARAB9A | |
| SCHEMBL18617604 | 0.74 | MAPT (0.47) | MAPTPOLBMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2174 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119715833-A | Method for detecting related substances in par Bai Xi or salt thereof | 北京斯利安药业有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119591540-A | Preparation method of piperaquine Bai Xili intermediate | 江苏希迪制药有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119569647-A | Buried material compound and application thereof in perovskite battery | 厦门紫金新能源新材料科技有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-118125974-A | Preparation method of 5- [ (4-ethylpiperazine-1-yl) methyl ] pyridin-2-amine | 山东铂源药业股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-117447463-A | Preparation and application of stable isotope labeled PBB3 compound | 深圳鼎邦生物科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-113150273-B | Preparation method of nitrogen-containing polymer | 中国科学院福建物质结构研究所 | 2024-01-23 | — | — | CN | claimed |
| WO-2024003798-A1 | A NOVEL PROCESS FOR THE PREPARATION OF 7 (4, 7- DIAZASPIRO [2.5] OCTAN-7-YL)-2-(2,8 DIMETHYLIMIDAZO[1,2-B] PYRID AZIN-6- YL) PYRIDO-4H-[1,2-A] PYRIMIDIN-4-ONE WITH NOVEL INTERMEDIATES | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2024-01-04 | — | — | WO | claimed |
| CN-117050096-A | Preparation method of risperidone | 杭州诺澳生物医药科技有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-113603639-B | Preparation method of 2-cyano-5-bromopyridine | 黑龙江立科新材料有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-115197130-B | Aryl urea derivative and preparation method and application thereof | 安徽医科大学 | 2023-06-27 | — | — | CN | claimed |
| CN-113636973-A | Industrial preparation method of 4- (6-aminopyridine-3-yl) piperazine-1-carboxylic acid tert-butyl ester | 山东铂源药业有限公司 | 2021-11-12 | — | — | CN | claimed |
| CN-113603639-A | Preparation method of 2-cyano-5-bromopyridine | 黑龙江立科新材料有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-113402513-A | Stability isotope labeled PM-PBB3 compound and preparation and application methods thereof | 深圳鼎邦生物科技有限公司 | 2021-09-17 | — | — | CN | claimed |
| CN-113150273-A | Preparation method of nitrogen-containing polymer | 中国科学院福建物质结构研究所 | 2021-07-23 | — | — | CN | claimed |
| CN-112645870-A | Green preparation method of anticancer drug palbocillin intermediate | 山东省青州荣军医院 | 2021-04-13 | — | — | CN | claimed |
| CN-112575044-A | Method for preparing CDK4/6 inhibitor key intermediate by chemical-enzymatic method | 山东铂源药业有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-111620852-A | 5-chloro-pyrimidine-2, 4-diamine compound and preparation method and application thereof | 南京迪维奥医药科技有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-108558745-A | A kind of pa wins the synthetic method of XiLin intermediate | 苏州莱克施德药业有限公司 | 2018-09-21 | — | — | CN | claimed |
| CN-106187867-B | A kind of preparation method of 2- nitros -5- bromopyridines | 济南贝莱尔化学科技有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-106187867-A | A kind of preparation method of 2 nitro 5 bromopyridines | 济南贝莱尔化学科技有限公司 | 2016-12-07 | — | — | CN | claimed |