Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12822749 | 0.94 | FFAR4 (0.32) | RARB | |
| SCHEMBL13654129 | 0.90 | RARB (0.34) | RARBHTR2AGRM2 | |
| SCHEMBL12718526 | 0.89 | APP (0.36) | RARBAPPHTR2AGRM2 | |
| SCHEMBL12822940 | 0.87 | RARB (0.36) | RARBHTR2AGRM2 | |
| SCHEMBL12822653 | 0.87 | CHKA (0.31) | — | |
| SCHEMBL12718442 | 0.87 | CHKA (0.31) | — | |
| SCHEMBL12823306 | 0.86 | BRD4 (0.30) | RARB | |
| SCHEMBL13586291 | 0.85 | RARB (0.34) | RARBHTR2AGRM2 | |
| SCHEMBL12994311 | 0.85 | RARB (0.37) | RARBHTR2AGRM2 | |
| SCHEMBL12821187 | 0.84 | PDE4A (0.34) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150966-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | チッソ株式会社 (JP) | 2009-12-17 | — | — | WO | disclosed |