SCHEMBL13586239

SCHEMBL13586239

CCOCc1ccc(CCc2ccc(-c3ccc(-c4ccc(OC)cc4)c(F)c3F)cc2)c(F)c1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.39
DAO P14920 1/20 0.39
ABCB1 P08183 1/20 0.38
FFAR1 O14842 2/20 0.37
FFAR4 Q5NUL3 1/20 0.37
CALM1 P0DP23 2/20 0.37
ESR1 P03372 1/20 0.36
CYP19A1 P11511 1/20 0.36
ESR2 Q92731 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35
TUBB2A Q13885 1/20 0.35
TUBB8 Q3ZCM7 1/20 0.35
TUBA3E Q6PEY2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13586332 1.00 MAOB (0.39) MAOBDAOABCB1FFAR1FFAR4
SCHEMBL13654044 0.92 FFAR1 (0.41) MAOBDAOABCB1FFAR1FFAR4
SCHEMBL13586550 0.91 MAOB (0.40) MAOBABCB1FFAR1FFAR4CALM1
SCHEMBL13654137 0.90 ABCB1 (0.34) ABCB1FFAR4CALM1CYP19A1ALOX5
SCHEMBL13586180 0.90 MAOB (0.38) MAOBABCB1FFAR1FFAR4CALM1
SCHEMBL13586462 0.88 MAOB (0.40) MAOBDAOFFAR1FFAR4CALM1
SCHEMBL13586287 0.88 MAOB (0.40) MAOBDAOABCB1FFAR1FFAR4
SCHEMBL12718487 0.87 ESR1 (0.37) FFAR1FFAR4CALM1ESR1CYP19A1
SCHEMBL12735610 0.87 FFAR4 (0.38) FFAR1FFAR4TAAR1CHKA
SCHEMBL12740121 0.87 FFAR4 (0.38) FFAR1FFAR4TAAR1CHKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009150966-A1 TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT チッソ株式会社 (JP) 2009-12-17 WO disclosed