Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12823910 | 1.00 | SYK (0.39) | SYKNAAACHRM1MAOBHTR1A | |
| SCHEMBL12908112 | 0.93 | MRGPRX4 (0.40) | SYKNAAAAPPFFAR1 | |
| SCHEMBL12994390 | 0.90 | FFAR1 (0.41) | SYKNAAACHRM1MAOBFFAR1 | |
| SCHEMBL12822902 | 0.89 | FEN1 (0.35) | CHRM1HTR1A | |
| SCHEMBL12823856 | 0.89 | FEN1 (0.35) | CHRM1HTR1A | |
| SCHEMBL12821314 | 0.87 | FFAR4 (0.38) | HTR1A | |
| SCHEMBL13586221 | 0.87 | FFAR4 (0.38) | HTR1A | |
| SCHEMBL12908284 | 0.86 | FFAR1 (0.40) | NAAAMAOBFFAR1 | |
| SCHEMBL12994783 | 0.86 | FFAR4 (0.35) | HTR1A | |
| SCHEMBL12821296 | 0.85 | FEN1 (0.37) | NAAAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150966-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | チッソ株式会社 (JP) | 2009-12-17 | — | — | WO | disclosed |