Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12823470 | 0.94 | TP53 (0.32) | TP53PDE2A | |
| SCHEMBL12823446 | 0.91 | PDE2A (0.32) | TP53PDE2A | |
| SCHEMBL12823915 | 0.91 | PDE2A (0.32) | TP53PDE2A | |
| SCHEMBL13586273 | 0.90 | TP53 (0.31) | TP53 | |
| SCHEMBL13586421 | 0.89 | TP53 (0.30) | TP53 | |
| SCHEMBL13586393 | 0.88 | TP53 (0.33) | TP53PDE2A | |
| SCHEMBL12821302 | 0.85 | CYP19A1 (0.33) | TP53PDE2A | |
| SCHEMBL12737642 | 0.85 | KDM1A (0.37) | — | |
| SCHEMBL12822980 | 0.85 | TP53 (0.32) | TP53PDE2A | |
| SCHEMBL13586348 | 0.84 | CYP2C9 (0.38) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150966-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | チッソ株式会社 (JP) | 2009-12-17 | — | — | WO | disclosed |