Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12821323 | 0.94 | APP (0.35) | S1PR5FFAR4FFAR1APPRXRA | |
| SCHEMBL12822535 | 0.89 | S1PR5 (0.35) | S1PR5FFAR4MRGPRX4FFAR1KDM1A | |
| SCHEMBL12907040 | 0.87 | MRGPRX4 (0.38) | S1PR5FFAR4MRGPRX4FFAR1S1PR1 | |
| SCHEMBL13586401 | 0.86 | KDM1A (0.38) | S1PR5FFAR4KDM1AS1PR1KDM4E | |
| SCHEMBL12822533 | 0.85 | FFAR4 (0.39) | S1PR5FFAR4FFAR1KDM1AS1PR1 | |
| SCHEMBL13586398 | 0.85 | FFAR1 (0.40) | FFAR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13586415 | 0.84 | FEN1 (0.34) | S1PR5FFAR4FFAR1 | |
| SCHEMBL12823858 | 0.84 | FFAR4 (0.34) | FFAR4MRGPRX4FFAR1RXRARXRB | |
| SCHEMBL13586403 | 0.84 | S1PR5 (0.34) | S1PR5FFAR4KDM1AS1PR1S1PR3 | |
| SCHEMBL12821318 | 0.84 | FFAR4 (0.34) | FFAR4MRGPRX4FFAR1RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150966-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | チッソ株式会社 (JP) | 2009-12-17 | — | — | WO | disclosed |