Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765726 | 0.94 | KDM1A (0.40) | KDM1ANAAAFPR2FFAR4PPARD | |
| SCHEMBL12717060 | 0.92 | FFAR4 (0.36) | KDM1ANAAAFFAR4KDM4EALDH1A1 | |
| SCHEMBL14765984 | 0.91 | KDM1A (0.38) | KDM1ANAAAFFAR4PPARGPPARA | |
| SCHEMBL12735142 | 0.91 | KDM1A (0.40) | KDM1ANAAAFPR2FFAR4KDM4E | |
| SCHEMBL12735126 | 0.90 | KDM1A (0.39) | KDM1ANAAAFPR2FFAR4 | |
| SCHEMBL12735128 | 0.89 | KDM1A (0.39) | KDM1ANAAAFPR2FFAR4S1PR1 | |
| SCHEMBL12735140 | 0.89 | KDM1A (0.39) | KDM1ANAAAFPR2FFAR4S1PR1 | |
| SCHEMBL12735132 | 0.87 | KDM1A (0.38) | KDM1ANAAAFPR2FFAR4 | |
| SCHEMBL10303104 | 0.87 | KDM1A (0.45) | KDM1ANAAAFPR2SGPL1S1PR1 | |
| SCHEMBL13586547 | 0.87 | FFAR4 (0.35) | NAAAFFAR4PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |
| WO-2009150966-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | チッソ株式会社 (JP) | 2009-12-17 | — | — | WO | disclosed |