Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL31376679 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL546955 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL451565 | 0.93 | — | — | |
| L-Lactic Acid SCHEMBL223995 | 0.93 | — | — | |
| L-Lactic Acid SCHEMBL223994 | 0.93 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL9052979 | 0.93 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL11294028 | 0.93 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL11222332 | 0.93 | — | — | |
| L-Lactic Acid SCHEMBL1359095 | 0.93 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL1700916 | 0.93 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10239792-B2 | Method of preparing ceramic powders | EESTOR, INC. (US) | 2019-03-26 | — | — | US | disclosed |
| US-20160023954-A1 | METHOD OF PREPARING CERAMIC POWDERS | EESTOR, INC. | 2016-01-28 | — | — | US | disclosed |
| US-8853116-B2 | Method of preparing ceramic powders | EESTOR, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| WO-2012115910-A2 | POWER SUPPLY AND POWER CONTROL CIRCUITRY | EESTOR, INC. (US) | 2012-08-30 | — | — | WO | disclosed |
| US-20120212987-A1 | POWER SUPPLY AND POWER CONTROL CIRCUITRY | EESTOR, INC. (US) | 2012-08-23 | — | — | US | disclosed |
| US-20110287925-A1 | METHOD OF PREPARING CERAMIC POWDERS USING AMMONIUM OXALATE | EESTOR, INC. (US) | 2011-11-24 | — | — | US | disclosed |
| US-7993611-B2 | Method of preparing ceramic powders using ammonium oxalate | EESTOR, INC. (US) | 2011-08-09 | — | — | US | disclosed |
| US-20110152060-A1 | METHOD OF PREPARING CERAMIC POWDERS USING CHELATE PRECURSORS | EESTOR, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| US-7914755-B2 | Method of preparing ceramic powders using chelate precursors | EESTOR, INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-20100285947-A1 | Method of Preparing Ceramic Powders | EESTOR, INC. (US) | 2010-11-11 | — | — | US | disclosed |
| US-20100285316-A1 | Method of Preparing Ceramic Powders | EESTOR, INC. (US) | 2010-11-11 | — | — | US | disclosed |
| US-20080031796-A1 | Method of preparing ceramic powders using ammonium oxalate | EESTOR, INC. | 2008-02-07 | — | — | US | disclosed |
| WO-2008017047-A2 | METHOD OF PREPARING CERAMIC POWDERS USING AMMONIUM OXALATE | EESTOR, INC. (US) | 2008-02-07 | — | — | WO | disclosed |