Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003869 | 0.91 | PRKAA2 (0.53) | CYP3A4 | |
| SCHEMBL13003251 | 0.90 | CYP3A4 (0.53) | CYP3A4 | |
| SCHEMBL8225792 | 0.90 | HRH1 (0.54) | CYP3A4 | |
| SCHEMBL13003575 | 0.89 | CYP3A4 (0.52) | CYP3A4 | |
| SCHEMBL8225777 | 0.88 | CYP3A4 (0.55) | CYP3A4 | |
| SCHEMBL13003871 | 0.87 | CYP3A4 (0.57) | CYP3A4 | |
| SCHEMBL13003595 | 0.85 | CYP3A4 (0.53) | CYP3A4 | |
| SCHEMBL13003580 | 0.85 | CYP3A4 (0.54) | CYP3A4 | |
| SCHEMBL8420507 | 0.85 | CYP3A4 (0.52) | CYP3A4 | |
| SCHEMBL13003882 | 0.85 | CYP3A4 (0.56) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902046-B1 | PIPERIDINE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORP (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007001975-A1 | PIPERIDINE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORPORATION (US) | 2007-01-04 | — | — | WO | disclosed |