Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13588981 | 0.90 | NPSR1 (0.58) | NPSR1ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL13588983 | 0.90 | NPSR1 (0.58) | NPSR1ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL4388900 | 0.90 | NPSR1 (0.58) | NPSR1ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL4391219 | 0.90 | NPSR1 (0.58) | NPSR1ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL4386504 | 0.89 | NPSR1 (0.58) | NPSR1ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL13588851 | 0.89 | NPSR1 (0.58) | NPSR1ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL3138460 | 0.89 | KDM4E (0.61) | NPSR1ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL13588856 | 0.89 | KDM4E (0.61) | NPSR1ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL13588982 | 0.88 | NPSR1 (0.72) | NPSR1ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL4391245 | 0.88 | NPSR1 (0.72) | NPSR1ALDH1A1TSHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629340-B2 | N-(6-membered aromatic ring)-amido anti-viral compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-08 | — | — | US | disclosed |