Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984669 | 0.87 | LRRK2 (0.45) | KCNN4 | |
| SCHEMBL984978 | 0.84 | KCNN4 (0.50) | KCNN4 | |
| SCHEMBL982816 | 0.84 | KCNN4 (0.46) | KCNN4 | |
| SCHEMBL986230 | 0.83 | KCNN4 (0.49) | KCNN4 | |
| SCHEMBL983000 | 0.83 | KCNN4 (0.52) | KCNN4 | |
| SCHEMBL983405 | 0.83 | KCNN4 (0.46) | KCNN4 | |
| SCHEMBL986447 | 0.83 | KCNN4 (0.46) | KCNN4 | |
| SCHEMBL985450 | 0.83 | KCNN4 (0.46) | KCNN4 | |
| SCHEMBL985181 | 0.83 | KCNN4 (0.46) | KCNN4 | |
| SCHEMBL986496 | 0.83 | KCNN4 (0.48) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004625-B1 | C-MET PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | VERTEX PHARMA (US) | 2009-12-30 | — | — | EP | disclosed |