Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.76 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.74 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364721 | 1.00 | DPP4 (0.76) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL20781026 | 0.86 | DPP4 (1.00) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8362642 | 0.83 | DPP4 (0.62) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8364641 | 0.82 | DPP4 (0.98) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8362641 | 0.82 | DPP4 (0.60) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL2667448 | 0.80 | DPP4 (0.75) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL10257660 | 0.80 | DPP4 (0.58) | DPP4DPP8DPP7 | |
| SCHEMBL8362698 | 0.80 | DPP4 (0.66) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL14187258 | 0.80 | DPP4 (0.77) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL2667530 | 0.79 | DPP4 (0.77) | DPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682550-B1 | SUBSTITUTED NAPHTHYRIDINONE DERIVATIVES | MERCK & CO INC (US) | 2009-12-23 | — | — | EP | disclosed |