Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.61 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8275266 | 0.94 | EPHX1 (0.53) | EPHX1NAAACA12CA1CA2 | |
| SCHEMBL26670015 | 0.78 | EPHX1 (0.64) | EPHX1NAAAHTTCYP2C19ALDH1A1 | |
| SCHEMBL967579 | 0.76 | EPHX1 (1.00) | EPHX1NAAAHTTCYP2C19ALDH1A1 | |
| SCHEMBL9422080 | 0.76 | EPHX1 (0.61) | EPHX1NAAACA12CA1CA2 | |
| SCHEMBL12785284 | 0.74 | EPHX1 (0.39) | EPHX1NAAACA12CA1CA2 | |
| SCHEMBL965658 | 0.73 | EPHX1 (0.96) | EPHX1NAAAHTTCYP2C19ALDH1A1 | |
| SCHEMBL29980822 | 0.73 | EPHX1 (0.68) | EPHX1NAAAHTTCYP2C19ALDH1A1 | |
| SCHEMBL11789894 | 0.72 | EPHX1 (0.56) | EPHX1NAAACA12CA1CA2 | |
| SCHEMBL11789890 | 0.72 | EPHX1 (0.56) | EPHX1NAAACA12CA1CA2 | |
| SCHEMBL18099455 | 0.71 | EPHX1 (0.42) | EPHX1NAAACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613587-B1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2009-12-30 | — | — | EP | disclosed |