Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16905239 | 0.86 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL30553428 | 0.76 | MEN1 (0.54) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL11972820 | 0.76 | MEN1 (0.54) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL29661959 | 0.76 | HSP90AA1 (0.70) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL7455899 | 0.76 | HSP90AA1 (0.70) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL1360928 | 0.75 | MEN1 (0.43) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL3027362 | 0.73 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL688655 | 0.73 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL29721839 | 0.73 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 | |
| SCHEMBL30604782 | 0.72 | NR4A2 (0.56) | HSP90AA1HSP90AB1IDO1PSMB5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067638-B2 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20090233962-A1 | Amide derivative and insecticide containing the same | MITSUI CHEMICALS, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-1911751-A1 | AMIDE DERIVATIVE AND PESTICIDE CONTAINING SUCH COMPOUND | Mitsui Chemicals, Inc. (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233962-A1 | Amide derivative and insecticide containing the same | CYP1A1, CYP4B1, CYP2E1 | HSP90AA1 951/4885HSP90AB1 1214/4885IDO1 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.