Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499171 | 0.90 | ACE (0.39) | PIM1BCAT1TDP1PPARA | |
| SCHEMBL4499168 | 0.90 | ACE (0.39) | PIM1BCAT1TDP1PPARA | |
| SCHEMBL4499170 | 0.90 | ACE (0.39) | PIM1BCAT1TDP1PPARA | |
| SCHEMBL13600880 | 0.80 | ELANE (0.39) | ELANEMETAP2MAPTMEN1KMT2A | |
| SCHEMBL13600967 | 0.76 | PIM1 (0.47) | MAPTALDH1A1PIM1LMNA | |
| SCHEMBL4496038 | 0.71 | PIM1 (0.58) | MAPTALDH1A1PIM1KMT2ABCAT1 | |
| SCHEMBL4496048 | 0.71 | PIM1 (0.58) | MAPTALDH1A1PIM1KMT2ABCAT1 | |
| SCHEMBL10618508 | 0.71 | PPARA (0.51) | ELANEMETAP2MAPTMEN1KMT2A | |
| SCHEMBL4495288 | 0.70 | SLC10A1 (0.37) | MEN1KMT2ATDP1SLC10A1PPARA | |
| SCHEMBL13600865 | 0.68 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |