Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13600977 | 1.00 | NAMPT (0.49) | NAMPTMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4492408 | 0.93 | NAMPT (0.49) | NAMPTMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4492412 | 0.93 | NAMPT (0.49) | NAMPTMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4492414 | 0.93 | NAMPT (0.49) | NAMPTMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4495793 | 0.85 | MAPT (0.47) | NAMPTMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4495796 | 0.85 | MAPT (0.47) | NAMPTMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4495788 | 0.85 | MAPT (0.47) | NAMPTMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4508951 | 0.83 | MAPT (0.51) | NAMPTMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4508944 | 0.83 | MAPT (0.51) | NAMPTMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL4508955 | 0.83 | MAPT (0.51) | NAMPTMAPTALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |