Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 15/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13608721 | 1.00 | GRM5 (0.41) | GRM5NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL13601436 | 0.91 | S1PR1 (0.43) | S1PR1 | |
| SCHEMBL13601406 | 0.91 | S1PR1 (0.43) | S1PR1 | |
| SCHEMBL13608820 | 0.91 | S1PR1 (0.43) | GRM5NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL13601398 | 0.91 | S1PR1 (0.43) | GRM5NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL13601410 | 0.89 | NR1H4 (0.44) | NPC1RAB9ASMN1; SMN2S1PR1 | |
| SCHEMBL13601412 | 0.86 | S1PR1 (0.43) | NPC1RAB9ASMN1; SMN2S1PR1 | |
| SCHEMBL13601425 | 0.86 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2S1PR1 | |
| SCHEMBL13601900 | 0.86 | S1PR1 (0.39) | GRM5NPC1RAB9AS1PR1 | |
| SCHEMBL13608470 | 0.86 | S1PR1 (0.39) | GRM5NPC1RAB9AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | GRM5 1282/4885NPC1 691/4885TP53 3116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.