Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 16/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601427 | 1.00 | NPC1 (0.45) | NPC1RAB9AS1PR1S1PR3MEN1 | |
| SCHEMBL13601397 | 0.93 | S1PR1 (0.46) | S1PR1S1PR3S1PR5S1PR4 | |
| Hydrochloric Acid SCHEMBL4513566 | 0.92 | S1PR1 (0.46) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL13601425 | 0.90 | NPC1 (0.43) | NPC1RAB9AS1PR1S1PR3MEN1 | |
| SCHEMBL13601434 | 0.89 | S1PR1 (0.42) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL13601411 | 0.89 | S1PR1 (0.42) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL13601414 | 0.89 | S1PR1 (0.46) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL13601428 | 0.88 | S1PR1 (0.44) | NPC1RAB9AS1PR1S1PR3S1PR5 | |
| SCHEMBL13601423 | 0.88 | S1PR1 (0.40) | NPC1RAB9AS1PR1S1PR3MEN1 | |
| SCHEMBL13601422 | 0.88 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | NPC1 691/4885RAB9A 3060/4885S1PR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.