Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601593 | 0.93 | CALCRL (0.66) | CALCRLRAMP1 | |
| SCHEMBL13601603 | 0.91 | CALCRL (0.67) | CALCRLRAMP1 | |
| SCHEMBL3353460 | 0.90 | CALCRL (0.70) | CALCRLRAMP1 | |
| SCHEMBL3353250 | 0.90 | CALCRL (0.71) | CALCRLRAMP1 | |
| SCHEMBL3353239 | 0.90 | CALCRL (0.71) | CALCRLRAMP1 | |
| SCHEMBL3351990 | 0.90 | CALCRL (0.66) | CALCRLRAMP1 | |
| SCHEMBL3356542 | 0.89 | CALCRL (0.69) | CALCRLRAMP1 | |
| SCHEMBL3356532 | 0.89 | CALCRL (0.69) | CALCRLRAMP1 | |
| SCHEMBL13601173 | 0.89 | CALCRL (0.63) | CALCRLRAMP1 | |
| SCHEMBL14541936 | 0.89 | CALCRL (0.63) | CALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625886-B2 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-01 | — | — | US | disclosed |
| US-7625886-B2 | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-01 | — | — | US | disclosed |