SCHEMBL13601818

SCHEMBL13601818

CC(C(=O)O)N(C)C(=O)c1ncc2cc(Oc3ccc(C(F)(F)F)cc3)ccc2c1O

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGLN2 Q96KS0 18/20 0.48
EGLN1 Q9GZT9 16/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13601815 0.89 EGLN2 (0.50) EGLN2EGLN1
SCHEMBL13601810 0.89 EGLN2 (0.58) EGLN2EGLN1
SCHEMBL13601808 0.88 EGLN2 (0.61) EGLN2EGLN1
SCHEMBL13601807 0.86 EGLN2 (0.48) EGLN2EGLN1
SCHEMBL13601812 0.83 EGLN2 (0.49) EGLN2EGLN1
SCHEMBL523387 0.82 EGLN2 (0.55) EGLN2EGLN1
SCHEMBL523386 0.82 EGLN2 (0.55) EGLN2EGLN1
SCHEMBL13601805 0.79 EGLN2 (0.46) EGLN2EGLN1
SCHEMBL29627762 0.76 EGLN2 (0.64) EGLN2EGLN1
SCHEMBL523875 0.75 EGLN1 (0.79) EGLN2EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629357-B2 Antihypoxic agents; adjust concentration of erythropoietin concentration in blood; strokes; antiepileptic agents; neurodegenerative disease ; liver disorders; antiischemic agents FIBROGEN, INC. (US) 2009-12-08 US disclosed
US-7629357-B2 Antihypoxic agents; adjust concentration of erythropoietin concentration in blood; strokes; antiepileptic agents; neurodegenerative disease ; liver disorders; antiischemic agents FIBROGEN, INC. (US) 2009-12-08 US disclosed