Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601840 | 0.88 | S1PR1 (0.52) | RAB9ATP53NPC1SMN1; SMN2S1PR1 | |
| SCHEMBL13601858 | 0.82 | S1PR1 (0.44) | RAB9ATP53NPC1SMN1; SMN2S1PR1 | |
| SCHEMBL4498851 | 0.78 | S1PR1 (0.56) | RAB9ATP53NPC1SMN1; SMN2S1PR1 | |
| SCHEMBL13601864 | 0.77 | S1PR1 (0.57) | RAB9ATP53NPC1SMN1; SMN2S1PR1 | |
| SCHEMBL13601863 | 0.77 | S1PR1 (0.52) | RAB9ATP53NPC1SMN1; SMN2S1PR1 | |
| SCHEMBL13601854 | 0.77 | S1PR1 (0.49) | RAB9ANPC1S1PR1S1PR3GAA | |
| SCHEMBL13601852 | 0.76 | S1PR1 (0.56) | RAB9ANPC1SMN1; SMN2S1PR1S1PR3 | |
| SCHEMBL13601885 | 0.76 | CA4 (0.52) | RAB9ATP53NPC1SMN1; SMN2S1PR1 | |
| SCHEMBL13601886 | 0.75 | S1PR1 (0.52) | RAB9ATP53NPC1SMN1; SMN2S1PR1 | |
| SCHEMBL13601872 | 0.75 | NPSR1 (0.55) | RAB9ANPC1SMN1; SMN2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | RAB9A 3060/4885TP53 3116/4885NPC1 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.