Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 17/20 | 0.61 |
| ▸ | FLT1 | P17948 | 14/20 | 0.61 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13604085 | 0.89 | KDR (0.46) | KDRFLT1PDCD1CD274 | |
| SCHEMBL13604116 | 0.85 | KDR (0.57) | KDRFLT1 | |
| SCHEMBL1346167 | 0.84 | GSK3A (0.45) | KDRFLT1PDCD1CD274TUBB4A | |
| SCHEMBL13604082 | 0.82 | KDR (0.79) | KDRFLT1 | |
| SCHEMBL1346522 | 0.82 | GSK3B (0.48) | KDRFLT1PDCD1CD274 | |
| SCHEMBL13603978 | 0.80 | KDR (0.56) | KDRFLT1PDCD1CD274 | |
| SCHEMBL1346528 | 0.79 | CA12 (0.39) | KDRFLT1PDCD1CD274 | |
| SCHEMBL1346864 | 0.79 | GSK3B (0.43) | KDRFLT1PDCD1CD274 | |
| SCHEMBL1345063 | 0.76 | GSK3A (0.52) | KDRFLT1PDCD1CD274 | |
| SCHEMBL1345025 | 0.75 | PDCD1 (0.45) | KDRFLT1PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128156-A1 | NOVEL OXADIAZOLE DERIVATIVES AND THIADIAZOLE DERIVATIVES HAVING NEOVASCULARIZATION INHIBITING ACTIVITY | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-02 | — | — | EP | disclosed |