Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.70 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.70 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1190005 | 0.94 | SLC22A12 (0.76) | SLC22A12SLC22A6SLC22A8KCNH2GPBAR1 | |
| SCHEMBL13037469 | 0.87 | SLC22A12 (0.87) | SLC22A12SLC22A6SLC22A8KCNH2GPBAR1 | |
| SCHEMBL1190015 | 0.85 | SLC22A12 (0.62) | SLC22A12SLC22A6SLC22A8GPBAR1TUBB4A | |
| SCHEMBL1190333 | 0.84 | SLC22A12 (0.64) | SLC22A12SLC22A6SLC22A8KCNH2GPBAR1 | |
| SCHEMBL1191465 | 0.84 | SLC22A12 (0.64) | SLC22A12SLC22A6SLC22A8KCNH2GPBAR1 | |
| SCHEMBL27101417 | 0.84 | SLC22A12 (0.80) | SLC22A12SLC22A6SLC22A8KCNH2GPBAR1 | |
| SCHEMBL13036486 | 0.84 | SLC22A12 (0.77) | SLC22A12SLC22A6SLC22A8KCNH2GPBAR1 | |
| SCHEMBL1190599 | 0.83 | SLC22A12 (0.69) | SLC22A12SLC22A6SLC22A8KCNH2GPBAR1 | |
| SCHEMBL1192001 | 0.83 | SLC22A12 (0.66) | SLC22A12SLC22A6SLC22A8KCNH2GPBAR1 | |
| Epaminurad SCHEMBL1191165 | 0.82 | SLC22A12 (1.00) | SLC22A12SLC22A6SLC22A8KCNH2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145456-A2 | HETEROCYCLIC DERIVATIVES | 주식회사 씨앤드씨신약연구소 (KR) | 2009-12-03 | — | — | WO | disclosed |