Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.48 |
| ▸ | GRM5 | P41594 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13606234 | 0.91 | CYP19A1 (0.53) | CYP19A1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13606341 | 0.91 | CYP19A1 (0.63) | CYP19A1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4465817 | 0.87 | CYP19A1 (0.57) | CYP19A1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4454767 | 0.83 | CYP19A1 (0.63) | CYP19A1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13606235 | 0.82 | FFAR4 (0.56) | CYP19A1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13606213 | 0.81 | FFAR4 (0.54) | CYP19A1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4462299 | 0.81 | HAO1 (0.55) | CYP19A1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13606339 | 0.78 | FFAR4 (0.53) | CYP19A1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4458510 | 0.78 | FFAR4 (0.52) | CYP19A1LMNATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13989138 | 0.78 | GRM5 (0.53) | CYP19A1LMNATDP1ALDH1A1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306115-A1 | Phenyl ethyne compounds | MERCK SHARP & DOHME CORP. | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306115-A1 | Phenyl ethyne compounds | DDT, CHRM3, CBR3 | CYP19A1 583/4885LMNA 4450/4885TDP1 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.