Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 9/20 | 0.60 |
| ▸ | TACR1 | P25103 | 7/20 | 0.42 |
| ▸ | CCR2 | P41597 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14309731 | 1.00 | CETP (0.60) | CETPTACR1CCR2KCNH2 | |
| SCHEMBL3943995 | 1.00 | CETP (0.60) | CETPTACR1CCR2KCNH2 | |
| SCHEMBL13608938 | 1.00 | CETP (0.60) | CETPTACR1CCR2KCNH2 | |
| SCHEMBL4070454 | 0.92 | CETP (0.59) | CETPTACR1CCR2 | |
| SCHEMBL13608951 | 0.92 | CETP (0.59) | CETPTACR1CCR2 | |
| SCHEMBL13608454 | 0.92 | CETP (0.70) | CETPTACR1CCR2 | |
| SCHEMBL4073494 | 0.91 | CETP (0.58) | CETPTACR1CCR2 | |
| SCHEMBL13608954 | 0.91 | CETP (0.58) | CETPTACR1CCR2 | |
| SCHEMBL13608923 | 0.91 | CETP (0.66) | CETPTACR1CCR2 | |
| SCHEMBL13608921 | 0.91 | CETP (0.66) | CETPTACR1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286790-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-11-19 | — | — | US | disclosed |
| US-20090286790-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286790-A1 | ORGANIC COMPOUNDS | CETP, NPC1, CES1 | CETP 1/4885TACR1 796/4885CCR2 2267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.