Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21494437 | 1.00 | TLR8 (0.46) | TLR8TLR7NOS1CYP1A2CYP2D6 | |
| SCHEMBL31658992 | 1.00 | TLR8 (0.46) | TLR8TLR7NOS1CYP1A2CYP2D6 | |
| SCHEMBL19317382 | 1.00 | TLR8 (0.46) | TLR8TLR7NOS1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL17654895 | 0.98 | TLR8 (0.45) | TLR8TLR7NOS1CYP1A2CYP2D6 | |
| SCHEMBL8126959 | 0.98 | TLR8 (0.47) | TLR8TLR7NOS1CYP1A2CYP2D6 | |
| SCHEMBL10263927 | 0.86 | KDM4E (0.45) | HPGDHSD17B10SYKKDM4EALDH1A1 | |
| SCHEMBL19306148 | 0.83 | PARP10 (0.44) | SYKKDM4EALDH1A1SMN1; SMN2AURKB | |
| SCHEMBL23085723 | 0.81 | HDAC3 (0.46) | CYP1A2CYP2D6CYP2C9SYKKDM4E | |
| SCHEMBL22401523 | 0.81 | HRH1 (0.59) | CYP1A2CYP2D6CYP2C9SYKKDM4E | |
| SCHEMBL2095025 | 0.81 | SMN1; SMN2 (0.44) | CYP1A2CYP2D6CYP2C9SYKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615641-B2 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2009-11-10 | — | — | US | disclosed |
| US-7615641-B2 | Long chain aliphatic alcohol derivatives and methods of making and using same | SINO PHARMACEUTICALS CORPORATION (CA) | 2009-11-10 | — | — | US | disclosed |