Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4378757 | 0.92 | MAPK14 (0.64) | MAPK14 | |
| SCHEMBL29594366 | 0.89 | MAPK14 (0.62) | MAPK14 | |
| SCHEMBL4382256 | 0.86 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL4381956 | 0.84 | MAPK14 (0.66) | MAPK14 | |
| SCHEMBL4381074 | 0.83 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL4390400 | 0.82 | MAPK14 (0.64) | MAPK14 | |
| SCHEMBL4387211 | 0.82 | MAPK14 (0.63) | MAPK14 | |
| SCHEMBL4385117 | 0.82 | MAPK14 (0.63) | MAPK14 | |
| SCHEMBL29594822 | 0.81 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL4383427 | 0.81 | MAPK14 (0.60) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |