Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5862351 | 0.90 | MAPK14 (0.72) | MAPK14 | |
| SCHEMBL4477258 | 0.89 | MAPK14 (0.72) | MAPK14 | |
| SCHEMBL5862528 | 0.83 | MAPK14 (0.67) | MAPK14 | |
| SCHEMBL4376115 | 0.83 | MAPK14 (0.69) | MAPK14 | |
| SCHEMBL29437793 | 0.82 | MAPK14 (0.74) | MAPK14 | |
| SCHEMBL4392896 | 0.82 | MAPK14 (0.70) | MAPK14 | |
| SCHEMBL5862320 | 0.81 | MAPK14 (0.67) | MAPK14 | |
| SCHEMBL13635214 | 0.81 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL5862313 | 0.81 | MAPK14 (0.64) | MAPK14 | |
| SCHEMBL5862636 | 0.81 | MAPK14 (0.66) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |