Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PDE1A | P54750 | 1/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12594012 | 0.86 | MAPK14 (0.70) | MCHR1MAPK14KCNH2 | |
| SCHEMBL5183913 | 0.85 | MAPK14 (0.59) | MCHR1MAPK14KCNH2 | |
| SCHEMBL4379071 | 0.85 | MAPK14 (0.68) | MCHR1MAPK14KCNH2MAOB | |
| SCHEMBL4382127 | 0.82 | MAPK14 (0.78) | MCHR1MAPK14KCNH2 | |
| SCHEMBL2176240 | 0.82 | MAPK14 (0.68) | MCHR1MAPK14KCNH2 | |
| SCHEMBL12487837 | 0.81 | MAPK14 (0.64) | MCHR1MAPK14KCNH2 | |
| SCHEMBL2179201 | 0.81 | MCHR1 (0.48) | MCHR1MAPK14KCNH2 | |
| SCHEMBL18347222 | 0.79 | PDE1A (0.47) | MAPK14PDE1APDE1BPDE1CDRD2 | |
| SCHEMBL4381779 | 0.79 | MAPK14 (0.65) | MCHR1MAPK14KCNH2MAOB | |
| SCHEMBL2174934 | 0.78 | MAPK14 (0.52) | MCHR1MAPK14KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |