Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.75 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.61 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.61 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.61 |
| ▸ | STRADA | Q7RTN6 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376585 | 0.89 | MAPK14 (0.82) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL29594306 | 0.89 | MAPK14 (0.82) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL4380029 | 0.88 | MAPK14 (0.84) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL29593933 | 0.86 | MAPK14 (0.84) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL4390394 | 0.86 | MAPK14 (0.84) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL4385548 | 0.86 | MAPK14 (1.00) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL29594335 | 0.86 | MAPK14 (1.00) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL4379121 | 0.84 | MAPK14 (0.66) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL27765711 | 0.83 | MAPK14 (0.79) | MAPK14ROCK2MAPK12MAPK11STRADA | |
| SCHEMBL4382967 | 0.83 | MAPK14 (0.88) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629363-B2 | antiinflammatory agent for treating asthma and chronic pulmonary inflammatory disease | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |