⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14366044 | 0.87 | SIRT2 (0.32) | — | |
| SCHEMBL13611124 | 0.80 | SIRT2 (0.32) | — | |
| SCHEMBL12236129 | 0.80 | SIRT2 (0.32) | — | |
| SCHEMBL12236104 | 0.80 | SIRT2 (0.32) | — | |
| SCHEMBL13611181 | 0.80 | SIRT2 (0.32) | — | |
| SCHEMBL13499207 | 0.80 | SIRT2 (0.32) | — | |
| SCHEMBL13611182 | 0.76 | SIRT2 (0.33) | — | |
| SCHEMBL13611169 | 0.73 | FURIN (0.31) | — | |
| SCHEMBL18288918 | 0.71 | SIRT2 (0.31) | — | |
| SCHEMBL13611172 | 0.68 | ALB (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622440-B2 | Cyclic natriuretic peptide constructs | PALATIN TECHNOLOGIES, INC. (US) | 2009-11-24 | — | — | US | disclosed |