SCHEMBL13611287

SCHEMBL13611287

CC(=O)[C@H]1CN(C2CCC2)[C@@H](CCCNC(=N)N)C(=O)N1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SIRT2 Q8IXJ6 6/20 0.32
▸ SIRT1 Q96EB6 6/20 0.32
▸ SIRT3 Q9NTG7 6/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18288918 0.96 SIRT2 (0.31) SIRT2SIRT1SIRT3
SCHEMBL13611182 0.91 SIRT2 (0.33) SIRT2SIRT1SIRT3
SCHEMBL13611181 0.87 SIRT2 (0.32) SIRT2SIRT1SIRT3
SCHEMBL13499207 0.87 SIRT2 (0.32) SIRT2SIRT1SIRT3
SCHEMBL13611124 0.87 SIRT2 (0.32) SIRT2SIRT1SIRT3
SCHEMBL13611169 0.87 FURIN (0.31) —
SCHEMBL12236129 0.87 SIRT2 (0.32) SIRT2SIRT1SIRT3
SCHEMBL12236104 0.87 SIRT2 (0.32) SIRT2SIRT1SIRT3
SCHEMBL12572125 0.83 SIRT2 (0.31) SIRT2SIRT1SIRT3
SCHEMBL12572147 0.83 SIRT2 (0.31) SIRT2SIRT1SIRT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7622440-B2 Cyclic natriuretic peptide constructs PALATIN TECHNOLOGIES, INC. (US) 2009-11-24 — — US disclosed
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