⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28644611 | 0.76 | — | — | |
| SCHEMBL436255 | 0.73 | — | — | |
| SCHEMBL17300477 | 0.66 | — | — | |
| SCHEMBL28035432 | 0.66 | TSHR (0.35) | — | |
| SCHEMBL103330 | 0.64 | — | — | |
| SCHEMBL18679618 | 0.63 | — | — | |
| SCHEMBL12294403 | 0.63 | — | — | |
| SCHEMBL19062774 | 0.63 | — | — | |
| SCHEMBL8382914 | 0.61 | — | — | |
| SCHEMBL20124947 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1967516-B1 | 4-(phenylamino)-6-oxo-1,6-dihydropyridazine-3-carboxamide derivatives as MEK inhibitors for the treatment of hyperproliferative diseases | ARRAY BIOPHARMA INC (US) | 2009-11-04 | — | — | EP | disclosed |