Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3013074 | 0.91 | CYP19A1 (0.50) | ABCB1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL3013079 | 0.91 | CYP19A1 (0.50) | ABCB1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL13441754 | 0.83 | CTDSP1 (0.54) | ABCB1RXRASIGMAR1ABCC1ABCG2 | |
| SCHEMBL12086822 | 0.83 | CTDSP1 (0.54) | ABCB1RXRASIGMAR1ABCC1ABCG2 | |
| SCHEMBL13604505 | 0.83 | CTDSP1 (0.54) | ABCB1RXRASIGMAR1ABCC1ABCG2 | |
| SCHEMBL20460341 | 0.82 | CYP19A1 (0.60) | NPC1RAB9AKDM4ELMNAPOLB | |
| SCHEMBL6758413 | 0.81 | MAPT (0.48) | ABCB1SIGMAR1ABCC1ABCG2KDM4E | |
| SCHEMBL6758414 | 0.81 | MAPT (0.48) | ABCB1SIGMAR1ABCC1ABCG2KDM4E | |
| SCHEMBL7122240 | 0.81 | MAPT (0.48) | ABCB1SIGMAR1ABCC1ABCG2KDM4E | |
| SCHEMBL5213783 | 0.78 | ABCB1 (0.60) | ABCB1RXRASIGMAR1ABCC1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632828-B2 | Gram-positive carbapenem antibacterials and processes for their preparation | FOB SYNTHESIS, INC. (US) | 2009-12-15 | — | — | US | disclosed |