Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | CYP2A13 | Q16696 | 5/20 | 0.44 |
| ▸ | GPR183 | P32249 | 2/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21974754 | 0.85 | NR1H2 (0.65) | NR1H2GPR183KMT2AKDM4EALDH1A1 | |
| SCHEMBL19233269 | 0.85 | NR1H2 (0.51) | NR1H2GPR183KDM4EALDH1A1ATM | |
| SCHEMBL19233516 | 0.83 | NR1H2 (0.52) | NR1H2GPR183KMT2AKDM4EALDH1A1 | |
| SCHEMBL2435935 | 0.80 | NR1H2 (0.70) | PDE3BPDE3AHIF1AEPAS1CYP2C9 | |
| SCHEMBL2800197 | 0.80 | PDE3B (0.55) | PDE3BPDE3AHIF1AEPAS1CYP2C9 | |
| SCHEMBL30900087 | 0.80 | NR1H2 (0.70) | PDE3BPDE3AHIF1AEPAS1CYP2C9 | |
| SCHEMBL10104471 | 0.80 | PDE3B (0.55) | PDE3BPDE3ACYP2C9ALOX15HSD17B10 | |
| SCHEMBL4657166 | 0.78 | PDE3B (0.51) | PDE3BPDE3AHIF1AEPAS1CYP2C9 | |
| SCHEMBL16510432 | 0.78 | CYP2C9 (0.58) | CYP2C9ALOX15HSD17B10CYP2A13ALDH3A1 | |
| SCHEMBL16510435 | 0.78 | MAPT (0.57) | GPR183KMT2AKDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968554-B2 | Modified drugs for use in liposomal nanoparticles | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2018-05-15 | — | — | US | disclosed |
| WO-2009141738-A2 | MODIFIED DRUGS FOR USE IN LIPOSOMAL NANOPARTICLES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2009-11-26 | — | — | WO | disclosed |