Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 16/20 | 0.36 |
| ▸ | F3 | P13726 | 16/20 | 0.36 |
| ▸ | F10 | P00742 | 12/20 | 0.36 |
| ▸ | F2 | P00734 | 12/20 | 0.36 |
| ▸ | F11 | P03951 | 8/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4761375 | 0.95 | NR1H4 (0.37) | F7F3F10F2F11 | |
| SCHEMBL2914274 | 0.93 | F7 (0.38) | F7F3F10F2F11 | |
| SCHEMBL4330201 | 0.89 | NR1H4 (0.37) | F7F3F10F2F11 | |
| SCHEMBL2914276 | 0.85 | F7 (0.37) | F7F3F10F2F11 | |
| SCHEMBL13613589 | 0.82 | F7 (0.39) | F7F3F10F2F11 | |
| SCHEMBL5006791 | 0.81 | F7 (0.39) | F7F3F10F2F11 | |
| SCHEMBL4330202 | 0.81 | NR1H4 (0.35) | F7F3F10F2F11 | |
| SCHEMBL2852064 | 0.81 | NR1H4 (0.37) | F7F3F10F2F11 | |
| SCHEMBL2853599 | 0.81 | F7 (0.36) | F7F3F10F2F11 | |
| SCHEMBL2915392 | 0.79 | F7 (0.44) | F7F3F10F2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622585-B2 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-24 | — | — | US | disclosed |