SCHEMBL13613795

SCHEMBL13613795

CCCCNC(=O)NCCOCCn1c(CCCC)nc2c(N)nc3ccccc3c21

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.65
TLR8 Q9NR97 7/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5739812 0.94 TLR7 (0.63) TLR7TLR8
SCHEMBL26352210 0.93 TLR7 (0.65) TLR7TLR8
SCHEMBL13613794 0.93 TLR7 (0.59) TLR7TLR8
SCHEMBL13613796 0.93 TLR7 (0.61) TLR7TLR8
SCHEMBL13613793 0.92 TLR7 (0.58) TLR7TLR8
SCHEMBL5352653 0.91 TLR7 (0.71) TLR7TLR8
SCHEMBL14592775 0.91 TLR7 (0.71) TLR7TLR8
SCHEMBL13613807 0.90 TLR7 (0.56) TLR7TLR8
SCHEMBL14592757 0.90 TLR7 (0.73) TLR7TLR8
SCHEMBL29475672 0.89 TLR7 (0.62) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612083-B2 Urea substituted imidazoquinoline ethers COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-11-03 US disclosed
US-7612083-B2 Urea substituted imidazoquinoline ethers COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-11-03 US disclosed
US-7214675-B2 Urea substituted imidazoquinoline ethers 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-08 US disclosed
US-7214675-B2 Urea substituted imidazoquinoline ethers 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-08 US disclosed