Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.80 |
| ▸ | ITGB2 | P05107 | 9/20 | 0.80 |
| ▸ | ICAM1 | P05362 | 9/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614896 | 0.90 | ITGAL (0.65) | ITGALITGB2ICAM1 | |
| SCHEMBL3841281 | 0.89 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL3841279 | 0.89 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL13614875 | 0.84 | ITGAL (0.65) | ITGALITGB2ICAM1 | |
| SCHEMBL3840807 | 0.84 | ITGAL (0.91) | ITGALITGB2ICAM1 | |
| SCHEMBL3840803 | 0.84 | ITGAL (0.91) | ITGALITGB2ICAM1 | |
| SCHEMBL13614165 | 0.79 | ITGAL (0.82) | ITGALITGB2ICAM1 | |
| SCHEMBL3843133 | 0.78 | ITGAL (0.81) | ITGALITGB2ICAM1 | |
| SCHEMBL3843132 | 0.78 | ITGAL (0.81) | ITGALITGB2ICAM1 | |
| SCHEMBL13614146 | 0.76 | ITGAL (0.82) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432700-B1 | SPIRO-HYDANTOIN COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | EP | disclosed |