Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.63 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18959507 | 0.90 | BCHE (0.55) | BCHEITGB3ITGA2BF2RDPP4 | |
| SCHEMBL27324185 | 0.90 | BCHE (0.55) | BCHEITGB3ITGA2BF2RDPP4 | |
| SCHEMBL1375400 | 0.85 | BCHE (0.62) | BCHEHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL12225623 | 0.82 | BCHE (0.56) | BCHEITGB3ITGA2BF2RDPP4 | |
| SCHEMBL10202194 | 0.82 | BCHE (0.56) | BCHEITGB3ITGA2BF2RDPP4 | |
| SCHEMBL12225627 | 0.82 | BCHE (0.56) | BCHEITGB3ITGA2BF2RDPP4 | |
| SCHEMBL10735407 | 0.82 | BCHE (0.62) | BCHEITGB3ITGA2BF2RPARP1 | |
| SCHEMBL15322067 | 0.81 | BCHE (0.57) | BCHEITGB3ITGA2BF2RDPP4 | |
| SCHEMBL15342480 | 0.80 | BCHE (0.44) | BCHEHTTHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL12424455 | 0.78 | BCHE (0.51) | BCHEDPP4KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432700-B1 | SPIRO-HYDANTOIN COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | EP | disclosed |