SCHEMBL13614300

SCHEMBL13614300

Cc1ccc(S(=O)(=O)N2C=CNC(=O)[C@H]2Cc2cn([C@H]3CCCc4cc(CNC5CCCC5)ccc43)nn2)cc1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BDKRB1 P46663 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4342555 1.00 BDKRB1 (0.62) BDKRB1
SCHEMBL4342550 1.00 BDKRB1 (0.62) BDKRB1
SCHEMBL13614315 0.94 BDKRB1 (0.54) BDKRB1
SCHEMBL4346251 0.94 BDKRB1 (0.54) BDKRB1
SCHEMBL4346256 0.94 BDKRB1 (0.54) BDKRB1
SCHEMBL4335042 0.93 BDKRB1 (0.53) BDKRB1
SCHEMBL13614322 0.93 BDKRB1 (0.53) BDKRB1
SCHEMBL4343921 0.93 BDKRB1 (0.53) BDKRB1
SCHEMBL13614321 0.93 BDKRB1 (0.53) BDKRB1
SCHEMBL4343918 0.93 BDKRB1 (0.53) BDKRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612060-B2 Triazoles and methods of use AMGEN INC. (US) 2009-11-03 US disclosed
US-7612060-B2 Triazoles and methods of use AMGEN INC. (US) 2009-11-03 US disclosed