Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13433617 | 0.88 | CYP11B1 (0.32) | — | |
| SCHEMBL10013945 | 0.87 | CYP11B1 (0.31) | — | |
| SCHEMBL14926653 | 0.86 | CYP11B1 (0.33) | PDE3BPDE3AHTR2AGRM2MEN1 | |
| SCHEMBL19303582 | 0.84 | PDE3B (0.39) | PDE3BPDE3AHTR2AGRM2MEN1 | |
| SCHEMBL27323466 | 0.84 | PDE3B (0.40) | PDE3BPDE3AHTR2AGRM2MEN1 | |
| SCHEMBL880992 | 0.83 | — | — | |
| SCHEMBL17035806 | 0.81 | CYP11B1 (0.34) | PDE3BPDE3A | |
| SCHEMBL21919557 | 0.80 | CYP11B1 (0.35) | HTR2AGRM2 | |
| SCHEMBL2741550 | 0.80 | CYP11B1 (0.35) | HTR2AGRM2 | |
| SCHEMBL15255976 | 0.80 | PDE3B (0.32) | PDE3BPDE3AHTR2AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116522-A1 | PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | Chisso Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |