⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514639 | 0.71 | — | — | |
| SCHEMBL31612401 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL6426118 | 0.61 | — | — | |
| SCHEMBL7939076 | 0.61 | — | — | |
| SCHEMBL9983847 | 0.61 | — | — | |
| SCHEMBL22802574 | 0.61 | — | — | |
| SCHEMBL9983522 | 0.61 | — | — | |
| Water SCHEMBL9579956 | 0.61 | — | — | |
| Hno SCHEMBL12727428 | 0.50 | — | — | |
| SCHEMBL583864 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170056528-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | MODERNATX, INC. | 2017-03-02 | — | — | US | disclosed |
| US-9428535-B2 | Modified nucleosides, nucleotides, and nucleic acids, and uses thereof | MODERNA THERAPEUTICS, INC. (US) | 2016-08-30 | — | — | US | disclosed |
| US-20140205566-A1 | CYCLIC NUCLEUOSIDE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2014-07-24 | — | — | US | disclosed |
| US-20130123481-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | modeRNA Therapeutics (US) | 2013-05-16 | — | — | US | disclosed |
| US-20130115272-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | modeRNA Therapeutics (US) | 2013-05-09 | — | — | US | disclosed |
| US-7612047-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20090076256-A1 | DEGRADATION-RESISTANT MONONUCLEOSIDE PHOSPHATE COMPOUNDS | DOUGLASS III JAMES G | 2009-03-19 | — | — | US | disclosed |
| US-7435724-B2 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICAL, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-7423143-B2 | Nucleic acid labeling compounds | AFFYMETRIX. INC. (US) | 2008-09-09 | — | — | US | disclosed |
| US-20070254298-A1 | ATROPISOMERS OF ASYMMETRIC XANTHENE FLUORESCENT DYES AND METHOD OF DNA SEQUENCING AND FRAGMENT ANALYSIS | APPLERA CORPORATION, APPLIED BIOSYSTEMS GROUP (US) | 2007-11-01 | — | — | US | disclosed |
| US-20070244068-A1 | Degradation-resistant mononucleoside phosphate compounds | INSPIRE PHARMACEUTICALS, INC. | 2007-10-18 | — | — | US | disclosed |
| US-7217550-B2 | Nucleotide-sugar-synthesizing enzymes from nonparasitic protists | NUTRINOVA, NUTRITION SPECIALTIES & FOOD INGREDIENTS, GMBH (DE) | 2007-05-15 | — | — | US | disclosed |