SCHEMBL13614620

SCHEMBL13614620

CCC1COC(CCc2ccc(C)c(F)c2)OC1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
DAO P14920 1/20 0.40
KCNH2 Q12809 2/20 0.32
MAPT P10636 1/20 0.31
PPARA Q07869 1/20 0.30
HCRTR1 O43613 1/20 0.30
HCRTR2 O43614 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23663912 0.81 SLC6A2 (0.32) SLC6A2SLC6A4SLC6A3
SCHEMBL23663946 0.78 RARB (0.33) SLC6A2SLC6A4SLC6A3
SCHEMBL23663896 0.78 CYP17A1 (0.38) SLC6A2SLC6A4SLC6A3
SCHEMBL23663963 0.77 MAOB (0.40)
SCHEMBL7779351 0.77 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3DAO
SCHEMBL7779344 0.77 SLC6A2 (0.36) SLC6A2SLC6A4SLC6A3DAO
SCHEMBL7782195 0.75 SPHK2 (0.36) SLC6A2SLC6A4SLC6A3DAOHCRTR1
SCHEMBL7782203 0.75 SPHK2 (0.36) SLC6A2SLC6A4SLC6A3DAOHCRTR1
SCHEMBL20259458 0.75 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3DAOCHRM5
SCHEMBL7781718 0.74 SPHK2 (0.37) SLC6A2SLC6A4SLC6A3DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2116522-A1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY Chisso Corporation (JP) 2009-11-11 EP disclosed