SCHEMBL13614726

SCHEMBL13614726

CC1CCC(c2ccc(-c3cc(F)c(I)c(F)c3)c(F)c2)CC1

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.41
ESR2 Q92731 1/20 0.40
CYP3A4 P08684 3/20 0.36
CYP2C9 P11712 2/20 0.36
APP P05067 2/20 0.36
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
PDK2 Q15119 1/20 0.31
AKR1A1 P14550 1/20 0.31
AKR1B1 P15121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91870 0.88 FASN (0.43) FASNESR2CYP3A4CYP2C9APP
SCHEMBL4431638 0.87 FASN (0.42) FASNESR2CYP3A4CYP2C9APP
SCHEMBL91927 0.87 FASN (0.42) FASNESR2CYP3A4CYP2C9APP
SCHEMBL20931102 0.86 FASN (0.42) FASNESR2CYP3A4CYP2C9APP
SCHEMBL14206983 0.85 FASN (0.41) FASNESR2CYP3A4CYP2C9APP
SCHEMBL19020104 0.85 FASN (0.46) FASNESR2CYP3A4CYP2C9APP
SCHEMBL14206989 0.85 FASN (0.41) FASNESR2CYP3A4CYP2C9APP
SCHEMBL14214748 0.85 ESR2 (0.47) FASNESR2CYP3A4CYP2C9APP
SCHEMBL13614719 0.85 FASN (0.43) FASNESR2CYP3A4CYP2C9APP
SCHEMBL12377041 0.84 FASN (0.49) FASNESR2CYP3A4CYP2C9APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017137145-A1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2017-08-17 WO disclosed
EP-2116522-A1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY Chisso Corporation (JP) 2009-11-11 EP disclosed