Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614180 | 0.87 | MEN1 (0.66) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL21642492 | 0.84 | MEN1 (0.62) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL17941874 | 0.82 | EGLN1 (0.62) | MEN1KMT2AHPGDALDH1A1GAA | |
| SCHEMBL7693830 | 0.80 | NPC1 (0.52) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL1644905 | 0.80 | MEN1 (0.61) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL6257044 | 0.78 | PLK1 (0.66) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL1483703 | 0.78 | KMT2A (0.62) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL30147578 | 0.78 | PLK1 (0.66) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL9792819 | 0.78 | KDM4E (0.64) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL13918749 | 0.77 | KDM4E (0.70) | RAB9ANPC1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432700-B1 | SPIRO-HYDANTOIN COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | EP | disclosed |