SCHEMBL13614970

SCHEMBL13614970

CCCCCC1COC(c2ccc(-c3ccc(-c4cc(F)c(CF)c(F)c4)c(F)c3)cc2)OC1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.31
RARA P10276 1/20 0.30
RARG P13631 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13615282 0.94 RARB (0.31) RARB
SCHEMBL881048 0.94
SCHEMBL13614966 0.93 RARB (0.32) RARB
SCHEMBL13614927 0.93 RARB (0.31) RARB
SCHEMBL881044 0.93 RARB (0.31) RARB
SCHEMBL13615224 0.92
SCHEMBL13615107 0.92 RARB (0.30) RARBRARARARGESR2
SCHEMBL19500360 0.90 RARB (0.32) RARBRARARARGESR2
SCHEMBL1815652 0.89 PDE3B (0.34) RARBRARARARGESR2
SCHEMBL19500347 0.87 ESR2 (0.34) RARBRARARARGESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2116522-A1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY Chisso Corporation (JP) 2009-11-11 EP disclosed