Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 3/20 | 0.30 |
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.30 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614954 | 0.96 | CYP3A4 (0.33) | CYP3A4CYP2C9APPCYP2D6CYP2C19 | |
| SCHEMBL19850829 | 0.89 | CYP3A4 (0.33) | CYP3A4CYP2C9APPCYP2D6CYP2C19 | |
| SCHEMBL16488490 | 0.85 | CYP3A4 (0.32) | CYP3A4CYP2C9APPCYP2D6CYP2C19 | |
| SCHEMBL13002548 | 0.85 | PDK2 (0.34) | CYP3A4CYP2C9APPCYP2D6CYP2C19 | |
| SCHEMBL19844716 | 0.85 | NPC1 (0.33) | CYP3A4CYP2C9APPCYP2D6CYP2C19 | |
| SCHEMBL18385880 | 0.84 | CYP3A4 (0.38) | CYP3A4CYP2C9APPCYP2D6CYP2C19 | |
| SCHEMBL12655810 | 0.84 | CYP3A4 (0.31) | CYP3A4CYP2C9APPCYP2D6CYP2C19 | |
| SCHEMBL14271073 | 0.83 | CYP3A4 (0.38) | CYP3A4CYP2C9APPCYP2D6CYP2C19 | |
| SCHEMBL13636640 | 0.83 | CYP3A4 (0.31) | CYP3A4CYP2C9APP | |
| SCHEMBL13614962 | 0.83 | CYP3A4 (0.37) | CYP3A4CYP2C9APPCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037818-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) | 2018-02-08 | — | — | US | disclosed |
| EP-2123623-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |
| EP-2116522-A1 | PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | Chisso Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |